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Cost and Cost-Effectiveness of Treating Childhood Cancer at Jimma Medical Center

BACKGROUND: More than 70% of childhood cancer patients die in Sub-Saharan African countries due to a lack of access. Additionally establishing a childhood cancer treatment service is perceived as expensive by the decision-makers of LMICs. However, there is a paucity of evidence on the actual cost an...

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Autores principales: Genemo, Idiris, Chala, Temesgen Kabeta, Hordofa, Diriba Fufa, Sinkie, Shimeles Ololo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257924/
https://www.ncbi.nlm.nih.gov/pubmed/37309357
http://dx.doi.org/10.2147/CEOR.S395170
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author Genemo, Idiris
Chala, Temesgen Kabeta
Hordofa, Diriba Fufa
Sinkie, Shimeles Ololo
author_facet Genemo, Idiris
Chala, Temesgen Kabeta
Hordofa, Diriba Fufa
Sinkie, Shimeles Ololo
author_sort Genemo, Idiris
collection PubMed
description BACKGROUND: More than 70% of childhood cancer patients die in Sub-Saharan African countries due to a lack of access. Additionally establishing a childhood cancer treatment service is perceived as expensive by the decision-makers of LMICs. However, there is a paucity of evidence on the actual cost and cost-effectiveness of this service in LMICs including Ethiopia. This study provides context-relevant evidence to consider childhood cancer treatment in the healthcare priority settings in Ethiopia and other LMICs. METHODS: Newly admitted case files of children for the year 2020/21 were reviewed. The cost was analyzed from the provider’s perspective. The effectiveness was calculated using DALY averted based on the 5 years of survival rates, which is estimated from the 1-year survival rate of Kaplan–Meier output. The do-nothing was our comparator, and we assumed no cost (zero cost) will be incurred for the comparator. To account for sensitivity analyses, we varied the discount rate, 5-year survival rate, and life expectancy. RESULTS: During the study period, 101 children were treated in the unit. The total annual and unit cost to give treatment to childhood cancer patients was estimated at $279,648 and $2769, respectively. The highest per-patient annual unit cost of treatment was Hodgkin’s lymphoma ($6252), while Retinoblastoma ($1520) was the least. The cost per DALY averted was $193, which is significantly less than Ethiopia’s GDP per capita ($936.3). The results remained very cost-effective in sensitivity analyses. CONCLUSION: Childhood cancer treatment is very cost-effective in Ethiopia as per WHO-CHOICE thresholds even in a conservative adjustment of assumptions. Therefore, to enhance and improve children’s health, childhood cancer should get a better concern in health priority.
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spelling pubmed-102579242023-06-12 Cost and Cost-Effectiveness of Treating Childhood Cancer at Jimma Medical Center Genemo, Idiris Chala, Temesgen Kabeta Hordofa, Diriba Fufa Sinkie, Shimeles Ololo Clinicoecon Outcomes Res Original Research BACKGROUND: More than 70% of childhood cancer patients die in Sub-Saharan African countries due to a lack of access. Additionally establishing a childhood cancer treatment service is perceived as expensive by the decision-makers of LMICs. However, there is a paucity of evidence on the actual cost and cost-effectiveness of this service in LMICs including Ethiopia. This study provides context-relevant evidence to consider childhood cancer treatment in the healthcare priority settings in Ethiopia and other LMICs. METHODS: Newly admitted case files of children for the year 2020/21 were reviewed. The cost was analyzed from the provider’s perspective. The effectiveness was calculated using DALY averted based on the 5 years of survival rates, which is estimated from the 1-year survival rate of Kaplan–Meier output. The do-nothing was our comparator, and we assumed no cost (zero cost) will be incurred for the comparator. To account for sensitivity analyses, we varied the discount rate, 5-year survival rate, and life expectancy. RESULTS: During the study period, 101 children were treated in the unit. The total annual and unit cost to give treatment to childhood cancer patients was estimated at $279,648 and $2769, respectively. The highest per-patient annual unit cost of treatment was Hodgkin’s lymphoma ($6252), while Retinoblastoma ($1520) was the least. The cost per DALY averted was $193, which is significantly less than Ethiopia’s GDP per capita ($936.3). The results remained very cost-effective in sensitivity analyses. CONCLUSION: Childhood cancer treatment is very cost-effective in Ethiopia as per WHO-CHOICE thresholds even in a conservative adjustment of assumptions. Therefore, to enhance and improve children’s health, childhood cancer should get a better concern in health priority. Dove 2023-06-07 /pmc/articles/PMC10257924/ /pubmed/37309357 http://dx.doi.org/10.2147/CEOR.S395170 Text en © 2023 Genemo et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Genemo, Idiris
Chala, Temesgen Kabeta
Hordofa, Diriba Fufa
Sinkie, Shimeles Ololo
Cost and Cost-Effectiveness of Treating Childhood Cancer at Jimma Medical Center
title Cost and Cost-Effectiveness of Treating Childhood Cancer at Jimma Medical Center
title_full Cost and Cost-Effectiveness of Treating Childhood Cancer at Jimma Medical Center
title_fullStr Cost and Cost-Effectiveness of Treating Childhood Cancer at Jimma Medical Center
title_full_unstemmed Cost and Cost-Effectiveness of Treating Childhood Cancer at Jimma Medical Center
title_short Cost and Cost-Effectiveness of Treating Childhood Cancer at Jimma Medical Center
title_sort cost and cost-effectiveness of treating childhood cancer at jimma medical center
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257924/
https://www.ncbi.nlm.nih.gov/pubmed/37309357
http://dx.doi.org/10.2147/CEOR.S395170
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