FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity

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Cellular exposure to free fatty acids (FFAs) is implicated in the pathogenesis of obesity-associated diseases. However, there are no scalable approaches to comprehensively assess the diverse FFAs circulating in human plasma. Furthermore, assessing how FFA-mediated processes interact with genetic ris...

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Detalles Bibliográficos
Autores principales: Wieder, Nicolas, Fried, Juliana Coraor, Kim, Choah, Sidhom, Eriene-Heidi, Brown, Matthew R., Marshall, Jamie L., Arevalo, Carlos, Dvela-Levitt, Moran, Kost-Alimova, Maria, Sieber, Jonas, Gabriel, Katlyn R., Pacheco, Julian, Clish, Clary, Abbasi, Hamdah Shafqat, Singh, Shantanu, Rutter, Justine C., Therrien, Martine, Yoon, Haejin, Lai, Zon Weng, Baublis, Aaron, Subramanian, Renuka, Devkota, Ranjan, Small, Jonnell, Sreekanth, Vedagopuram, Han, Myeonghoon, Lim, Donghyun, Carpenter, Anne E., Flannick, Jason, Finucane, Hilary, Haigis, Marcia C., Claussnitzer, Melina, Sheu, Eric, Stevens, Beth, Wagner, Bridget K., Choudhary, Amit, Shaw, Jillian L., Pablo, Juan Lorenzo, Greka, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257950/
https://www.ncbi.nlm.nih.gov/pubmed/37075753
http://dx.doi.org/10.1016/j.cmet.2023.03.018
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