DNMT1 regulates polarization of macrophage-induced intervertebral disc degeneration by modulating SIRT6 expression and promoting pyroptosis in vivo

Background: Intervertebral disc degeneration (IDD) is a complex phenomenon and a multifactorial degenerative disease that creates a heavy economic burden on health systems globally. Currently, there is no specific treatment proven to be effective in reversing and delaying the progression of IDD. Met...

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Detalles Bibliográficos
Autores principales: Hou, Yang, Shi, Jiangang, Guo, Yongfei, Shi, Guodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258003/
https://www.ncbi.nlm.nih.gov/pubmed/37199639
http://dx.doi.org/10.18632/aging.204729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258003/
https://www.ncbi.nlm.nih.gov/pubmed/37199639
http://dx.doi.org/10.18632/aging.204729

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