Stress granules sequester Alzheimer’s disease-associated gene transcripts and regulate disease-related neuronal proteostasis

Environmental and physiological stresses can accelerate Alzheimer’s disease (AD) pathogenesis. Under stress, a cytoplasmic membraneless structure termed a stress granule (SG) is formed and is associated with various neurodegenerative disorders, including AD. SGs contain translationally arrested mRNA...

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Detalles Bibliográficos
Autores principales: Sato, Kaoru, Takayama, Ken-ichi, Inoue, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258020/
https://www.ncbi.nlm.nih.gov/pubmed/37219408
http://dx.doi.org/10.18632/aging.204737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258020/
https://www.ncbi.nlm.nih.gov/pubmed/37219408
http://dx.doi.org/10.18632/aging.204737

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