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Stress granules sequester Alzheimer’s disease-associated gene transcripts and regulate disease-related neuronal proteostasis
Environmental and physiological stresses can accelerate Alzheimer’s disease (AD) pathogenesis. Under stress, a cytoplasmic membraneless structure termed a stress granule (SG) is formed and is associated with various neurodegenerative disorders, including AD. SGs contain translationally arrested mRNA...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258020/ https://www.ncbi.nlm.nih.gov/pubmed/37219408 http://dx.doi.org/10.18632/aging.204737 |