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Immune checkpoint blockade therapy for BRAF mutant metastatic colorectal cancer: the efficacy, new strategies, and potential biomarkers
BRAF mutant metastatic colorectal cancer has long been considered a tumor with a poor prognosis and a poor response to chemotherapy. Despite the efficacy of targeted therapy with multi-targeted blockade of the mitogen-activated protein kinase (MAPK) signaling pathway has brought a glimmer of hope to...
Autores principales: | Zhong, Jie, Sun, Zijian, Li, Sheng, Yang, Liu, Cao, Yuepeng, Bao, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258190/ https://www.ncbi.nlm.nih.gov/pubmed/37302081 http://dx.doi.org/10.1007/s12672-023-00718-y |
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