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HIV-1 resistance against dolutegravir fluctuates rapidly alongside erratic treatment adherence: a case report

OBJECTIVES: We report a case of incomplete HIV-1 suppression on a dolutegravir, lamivudine, and abacavir single-tablet regimen with the emergence of the H51Y and G118R integrase resistance mutations. METHODS: Integrase sequencing was performed retrospectively by Sanger and next-generation sequencing...

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Detalles Bibliográficos
Autores principales: van Kampen, Jeroen J.A., Pham, Hanh Thi, Yoo, Sunbin, Overmars, Ronald J., Lungu, Cynthia, Mahmud, Rizwan, Schurink, Carolina A.M., van Boheemen, Sander, Gruters, Rob A., Fraaij, Pieter L.A., Burger, David M., Voermans, Jolanda J.C., Rokx, Casper, van de Vijver, David A.M.C., Mesplède, Thibault
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258191/
https://www.ncbi.nlm.nih.gov/pubmed/36347497
http://dx.doi.org/10.1016/j.jgar.2022.11.001