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Relationship between polygenic risk scores and symptom dimensions of schizophrenia and schizotypy in multiplex families with schizophrenia

BACKGROUND: Psychotic disorders and schizotypal traits aggregate in the relatives of probands with schizophrenia. It is currently unclear how variability in symptom dimensions in schizophrenia probands and their relatives is associated with polygenic liability to psychiatric disorders. AIMS: To inve...

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Detalles Bibliográficos
Autores principales: Ahangari, Mohammad, Bustamante, Daniel, Kirkpatrick, Robert, Nguyen, Tan-Hoang, Verrelli, Brian C., Fanous, Ayman, Kendler, Kenneth S., Webb, Bradley T., Bacanu, Silviu-Alin, Riley, Brien P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258219/
https://www.ncbi.nlm.nih.gov/pubmed/36503694
http://dx.doi.org/10.1192/bjp.2022.179