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Short-term use of CGM in youth onset type 2 diabetes is associated with behavioral modifications

BACKGROUND: Continuous glucose monitoring (CGM) is beneficial to glycemic control in youth with type 1 diabetes (T1D) and adults with type 2 diabetes (T2D); however, studies in youth with T2D are limited. OBJECTIVE: Determine if 10-day trial CGM use in youth with T2D improves glycemic control and be...

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Autores principales: Manfredo, Jacquelyn, Lin, Tyger, Gupta, Radhika, Abiola, Kai, West, Margaret, Busin, Kelly, Tracey, Julia, Brown, Elizabeth A., Magge, Sheela N., Wolf, Risa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258317/
https://www.ncbi.nlm.nih.gov/pubmed/37313442
http://dx.doi.org/10.3389/fendo.2023.1182260
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author Manfredo, Jacquelyn
Lin, Tyger
Gupta, Radhika
Abiola, Kai
West, Margaret
Busin, Kelly
Tracey, Julia
Brown, Elizabeth A.
Magge, Sheela N.
Wolf, Risa M.
author_facet Manfredo, Jacquelyn
Lin, Tyger
Gupta, Radhika
Abiola, Kai
West, Margaret
Busin, Kelly
Tracey, Julia
Brown, Elizabeth A.
Magge, Sheela N.
Wolf, Risa M.
author_sort Manfredo, Jacquelyn
collection PubMed
description BACKGROUND: Continuous glucose monitoring (CGM) is beneficial to glycemic control in youth with type 1 diabetes (T1D) and adults with type 2 diabetes (T2D); however, studies in youth with T2D are limited. OBJECTIVE: Determine if 10-day trial CGM use in youth with T2D improves glycemic control and behavioral modifications. METHODS: Youth with T2D > 3 months, on insulin, with no prior CGM use were enrolled. Staff placed CGM and provided education. Participants received 5-day and 10-day follow-up phone calls to review CGM data, behavioral modifications, and adjust insulin doses as needed. We compared 5-day to 10-day TIR, and baseline to 3-6 month HbA1c via paired t-test. RESULTS: Participants (n=41) had median age of 16.2 y, were 61% female, 81% NH Black, median diabetes duration of 0.8 y, and baseline HbA1c of 10.3%. A majority had household income<$50,000 (81%) and parental education level of HS or less (73%). Average 5-day TIR 49% was similar to 10-day TIR 51% (p=0.62). There was no change in HbA1c after 3-6 months (10.2% v 10.3%, p=0.89). Nineteen participants completed full 10-day CGM use; of those, 84% wanted a CGM long-term. Adolescents reported behavioral changes including increased blood sugar checks, increased insulin administration and overall improved diabetes management. CONCLUSION: Although 10-day CGM use did not impact short-term or long-term glycemic control in youth with T2D, most participants reported behavioral changes and wanted to continue using CGM. Future studies with longer use of CGM may clarify the potential impact of CGM in youth with T2D.
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spelling pubmed-102583172023-06-13 Short-term use of CGM in youth onset type 2 diabetes is associated with behavioral modifications Manfredo, Jacquelyn Lin, Tyger Gupta, Radhika Abiola, Kai West, Margaret Busin, Kelly Tracey, Julia Brown, Elizabeth A. Magge, Sheela N. Wolf, Risa M. Front Endocrinol (Lausanne) Endocrinology BACKGROUND: Continuous glucose monitoring (CGM) is beneficial to glycemic control in youth with type 1 diabetes (T1D) and adults with type 2 diabetes (T2D); however, studies in youth with T2D are limited. OBJECTIVE: Determine if 10-day trial CGM use in youth with T2D improves glycemic control and behavioral modifications. METHODS: Youth with T2D > 3 months, on insulin, with no prior CGM use were enrolled. Staff placed CGM and provided education. Participants received 5-day and 10-day follow-up phone calls to review CGM data, behavioral modifications, and adjust insulin doses as needed. We compared 5-day to 10-day TIR, and baseline to 3-6 month HbA1c via paired t-test. RESULTS: Participants (n=41) had median age of 16.2 y, were 61% female, 81% NH Black, median diabetes duration of 0.8 y, and baseline HbA1c of 10.3%. A majority had household income<$50,000 (81%) and parental education level of HS or less (73%). Average 5-day TIR 49% was similar to 10-day TIR 51% (p=0.62). There was no change in HbA1c after 3-6 months (10.2% v 10.3%, p=0.89). Nineteen participants completed full 10-day CGM use; of those, 84% wanted a CGM long-term. Adolescents reported behavioral changes including increased blood sugar checks, increased insulin administration and overall improved diabetes management. CONCLUSION: Although 10-day CGM use did not impact short-term or long-term glycemic control in youth with T2D, most participants reported behavioral changes and wanted to continue using CGM. Future studies with longer use of CGM may clarify the potential impact of CGM in youth with T2D. Frontiers Media S.A. 2023-05-29 /pmc/articles/PMC10258317/ /pubmed/37313442 http://dx.doi.org/10.3389/fendo.2023.1182260 Text en Copyright © 2023 Manfredo, Lin, Gupta, Abiola, West, Busin, Tracey, Brown, Magge and Wolf https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Manfredo, Jacquelyn
Lin, Tyger
Gupta, Radhika
Abiola, Kai
West, Margaret
Busin, Kelly
Tracey, Julia
Brown, Elizabeth A.
Magge, Sheela N.
Wolf, Risa M.
Short-term use of CGM in youth onset type 2 diabetes is associated with behavioral modifications
title Short-term use of CGM in youth onset type 2 diabetes is associated with behavioral modifications
title_full Short-term use of CGM in youth onset type 2 diabetes is associated with behavioral modifications
title_fullStr Short-term use of CGM in youth onset type 2 diabetes is associated with behavioral modifications
title_full_unstemmed Short-term use of CGM in youth onset type 2 diabetes is associated with behavioral modifications
title_short Short-term use of CGM in youth onset type 2 diabetes is associated with behavioral modifications
title_sort short-term use of cgm in youth onset type 2 diabetes is associated with behavioral modifications
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258317/
https://www.ncbi.nlm.nih.gov/pubmed/37313442
http://dx.doi.org/10.3389/fendo.2023.1182260
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