Cargando…
An MVA-based vector expressing cell-free ISG15 increases IFN-I production and improves HIV-1-specific CD8 T cell immune responses
The human immunodeficiency virus (HIV), responsible of the Acquired Immune Deficiency Syndrome (AIDS), continues to be a major global public health issue with any cure or vaccine available. The Interferon-stimulated gene 15 (ISG15) encodes a ubiquitin-like protein that is induced by interferons and...
Autores principales: | Falqui, Michela, Perdiguero, Beatriz, Coloma, Rocio, Albert, Manuel, Marcos-Villar, Laura, McGrail, Joseph Patrick, Sorzano, Carlos Óscar S., Esteban, Mariano, Gómez, Carmen Elena, Guerra, Susana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258332/ https://www.ncbi.nlm.nih.gov/pubmed/37313341 http://dx.doi.org/10.3389/fcimb.2023.1187193 |
Ejemplares similares
-
ISG15 Is Required for the Dissemination of Vaccinia Virus Extracellular Virions
por: Bécares, Martina, et al.
Publicado: (2023) -
Induction of Broad and Polyfunctional HIV-1-Specific T Cell Responses by the Multiepitopic Protein TMEP-B Vectored by MVA Virus
por: Perdiguero, Beatriz, et al.
Publicado: (2019) -
ISG15, a Small Molecule with Huge Implications: Regulation of Mitochondrial Homeostasis
por: Albert, Manuel, et al.
Publicado: (2018) -
Enhancement of the HIV-1-Specific Immune Response Induced by an mRNA Vaccine through Boosting with a Poxvirus MVA Vector Expressing the Same Antigen
por: Gómez, Carmen Elena, et al.
Publicado: (2021) -
A Novel MVA-Based HIV Vaccine Candidate (MVA-gp145-GPN) Co-Expressing Clade C Membrane-Bound Trimeric gp145 Env and Gag-Induced Virus-Like Particles (VLPs) Triggered Broad and Multifunctional HIV-1-Specific T Cell and Antibody Responses
por: Perdiguero, Beatriz, et al.
Publicado: (2019)