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LncRNAs and regulated cell death in tumor cells
Regulated Cell Death (RCD) is a mode of cell death that occurs through drug or genetic intervention. The regulation of RCDs is one of the significant reasons for the long survival time of tumor cells and poor prognosis of patients. Long non-coding RNAs (lncRNAs) which are involved in the regulation...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258353/ https://www.ncbi.nlm.nih.gov/pubmed/37313458 http://dx.doi.org/10.3389/fonc.2023.1170336 |
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author | Wu, Yingying Wen, Xiaoling Xia, Yufang Yu, Xiao Lou, Yanhui |
author_facet | Wu, Yingying Wen, Xiaoling Xia, Yufang Yu, Xiao Lou, Yanhui |
author_sort | Wu, Yingying |
collection | PubMed |
description | Regulated Cell Death (RCD) is a mode of cell death that occurs through drug or genetic intervention. The regulation of RCDs is one of the significant reasons for the long survival time of tumor cells and poor prognosis of patients. Long non-coding RNAs (lncRNAs) which are involved in the regulation of tumor biological processes, including RCDs occurring on tumor cells, are closely related to tumor progression. In this review, we describe the mechanisms of eight different RCDs which contain apoptosis, necroptosis, pyroptosis, NETosis, entosis, ferroptosis, autosis and cuproptosis. Meanwhile, their respective roles in the tumor are aggregated. In addition, we outline the literature that is related to the regulatory relationships between lncRNAs and RCDs in tumor cells, which is expected to provide new ideas for tumor diagnosis and treatment. |
format | Online Article Text |
id | pubmed-10258353 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-102583532023-06-13 LncRNAs and regulated cell death in tumor cells Wu, Yingying Wen, Xiaoling Xia, Yufang Yu, Xiao Lou, Yanhui Front Oncol Oncology Regulated Cell Death (RCD) is a mode of cell death that occurs through drug or genetic intervention. The regulation of RCDs is one of the significant reasons for the long survival time of tumor cells and poor prognosis of patients. Long non-coding RNAs (lncRNAs) which are involved in the regulation of tumor biological processes, including RCDs occurring on tumor cells, are closely related to tumor progression. In this review, we describe the mechanisms of eight different RCDs which contain apoptosis, necroptosis, pyroptosis, NETosis, entosis, ferroptosis, autosis and cuproptosis. Meanwhile, their respective roles in the tumor are aggregated. In addition, we outline the literature that is related to the regulatory relationships between lncRNAs and RCDs in tumor cells, which is expected to provide new ideas for tumor diagnosis and treatment. Frontiers Media S.A. 2023-05-29 /pmc/articles/PMC10258353/ /pubmed/37313458 http://dx.doi.org/10.3389/fonc.2023.1170336 Text en Copyright © 2023 Wu, Wen, Xia, Yu and Lou https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Wu, Yingying Wen, Xiaoling Xia, Yufang Yu, Xiao Lou, Yanhui LncRNAs and regulated cell death in tumor cells |
title | LncRNAs and regulated cell death in tumor cells |
title_full | LncRNAs and regulated cell death in tumor cells |
title_fullStr | LncRNAs and regulated cell death in tumor cells |
title_full_unstemmed | LncRNAs and regulated cell death in tumor cells |
title_short | LncRNAs and regulated cell death in tumor cells |
title_sort | lncrnas and regulated cell death in tumor cells |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258353/ https://www.ncbi.nlm.nih.gov/pubmed/37313458 http://dx.doi.org/10.3389/fonc.2023.1170336 |
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