Microtubule Acetylation-Specific Inhibitors Induce Cell Death and Mitotic Arrest via JNK/AP-1 Activation in Triple-Negative Breast Cancer Cells

Microtubule acetylation has been proposed as a marker of highly heterogeneous and aggressive triple-negative breast cancer (TNBC). The novel microtubule acetylation inhibitors GM-90257 and GM-90631 (GM compounds) cause TNBC cancer cell death but the underlying mechanisms are currently unknown. In th...

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Detalles Bibliográficos
Autores principales: Ahn, Suyeon, Kwon, Ahreum, Oh, Youngsoo, Rhee, Sangmyung, Song, Woo Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258459/
https://www.ncbi.nlm.nih.gov/pubmed/36794420
http://dx.doi.org/10.14348/molcells.2023.2192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258459/
https://www.ncbi.nlm.nih.gov/pubmed/36794420
http://dx.doi.org/10.14348/molcells.2023.2192

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