Age‐associated change in pyruvate metabolism investigated with hyperpolarized (13)C‐MRI of the human brain

In this study, hyperpolarized (13)C MRI (HP‐(13)C MRI) was used to investigate changes in the uptake and metabolism of pyruvate with age. Hyperpolarized (13)C‐pyruvate was administered to healthy aging individuals (N = 35, ages 21–77) and whole‐brain spatial distributions of (13)C‐lactate and (13)C‐...

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Detalles Bibliográficos
Autores principales: Uthayakumar, Biranavan, Soliman, Hany, Bragagnolo, Nadia D., Cappelletto, Nicole I. C., Lee, Casey Y., Geraghty, Benjamin, Chen, Albert P., Perks, William J., Ma, Nathan, Heyn, Chris, Endre, Ruby, MacIntosh, Bradley J., Stanisz, Greg J., Black, Sandra E., Cunningham, Charles H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258534/
https://www.ncbi.nlm.nih.gov/pubmed/37219519
http://dx.doi.org/10.1002/hbm.26329

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