Cargando…

Effects of Memantine on the Spontaneous Firing Frequency of Hippocampal CA1 Pyramidal Neurons in Intact and Alzheimer Rat Model: An Electrophysiological Study

INTRODUCTION: Memantine (MEM) is a noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist clinically used for the treatment of Alzheimer disease (AD) in mild to severe conditions. The present study was conducted to investigate the effects of memantine on the spontaneous firing frequency of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zamani, Nastaran, Moazedi, Ahmad Ali, Afarinesh Khaki, Mohamad Reza, Pourmehdi Boroujeni, Mehdi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tehran University of Medical Sciences 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258597/ https://www.ncbi.nlm.nih.gov/pubmed/37313029 http://dx.doi.org/10.32598/bcn.2021.1970.1

Ejemplares similares

Persistent Firing in Hippocampal CA1 Pyramidal Cells in Young and Aged Rats
por: Brahimi, Yacine, et al.
Publicado: (2023)

Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells
por: Arboit, Alberto, et al.
Publicado: (2020)

An Adaptive Generalized Leaky Integrate-and-Fire Model for Hippocampal CA1 Pyramidal Neurons and Interneurons
por: Marasco, Addolorata, et al.
Publicado: (2023)

Effects of Donepezil Hydrochloride on Neuronal Response of Pyramidal Neurons of the CA1 Hippocampus in Rat Model of Alzheimer’s Disease
por: Eskandary, Azade, et al.
Publicado: (2019)

Electrophysiological Effects of SKF83959 on Hippocampal CA1 Pyramidal Neurons: Potential Mechanisms for the Drug's Neuroprotective Effects
por: Chu, Hong-Yuan, et al.
Publicado: (2010)

Noradrenergic Suppression of Persistent Firing in Hippocampal CA1 Pyramidal Cells through cAMP-PKA Pathway
por: Valero-Aracama, Maria Jesus, et al.
Publicado: (2021)

Dopamine D(3) Receptors Inhibit Hippocampal Gamma Oscillations by Disturbing CA3 Pyramidal Cell Firing Synchrony
por: Lemercier, Clément E., et al.
Publicado: (2016)

Heterogeneity in Kv2 Channel Expression Shapes Action Potential Characteristics and Firing Patterns in CA1 versus CA2 Hippocampal Pyramidal Neurons
por: Palacio, Stephanie, et al.
Publicado: (2017)

Variable Dendritic Integration in Hippocampal CA3 Pyramidal Neurons
por: Makara, Judit K., et al.
Publicado: (2013)

Electrophysiological Characterization of Regular and Burst Firing Pyramidal Neurons of the Dorsal Subiculum in an Angelman Syndrome Mouse Model
por: Rayi, Prudhvi Raj, et al.
Publicado: (2021)

Weak Sinusoidal Electric Fields Entrain Spontaneous Ca Transients in the Dendritic Tufts of CA1 Pyramidal Cells in Rat Hippocampal Slice Preparations
por: Maeda, Kazuma, et al.
Publicado: (2015)

Hippocampal CA1 pyramidal cells form functionally distinct sublayers
por: Mizuseki, Kenji, et al.
Publicado: (2011)

Electrophysiological Properties of CA1 Pyramidal Neurons along the Longitudinal Axis of the Mouse Hippocampus
por: Milior, Giampaolo, et al.
Publicado: (2016)

The Cannabinoid-Like Compound, VSN16R, Acts on Large Conductance, Ca(2+)-Activated K(+) Channels to Modulate Hippocampal CA1 Pyramidal Neuron Firing
por: Tabatabaee, Setareh, et al.
Publicado: (2019)

Sub-Millisecond Firing Synchrony of Closely Neighboring Pyramidal Neurons in Hippocampal CA1 of Rats During Delayed Non-Matching to Sample Task
por: Takahashi, Susumu, et al.
Publicado: (2009)

CBCT Evaluation of Bony Nasal Pyramid Dimensions in Iranian Population: A Comparative Study with Ethnic Groups
por: Zamani Naser, Asieh, et al.
Publicado: (2014)

Repetitive mild traumatic brain injury induces persistent alterations in spontaneous synaptic activity of hippocampal CA1 pyramidal neurons
por: Langlois, Ludovic D., et al.
Publicado: (2022)

Extreme Neuroplasticity of Hippocampal CA1 Pyramidal Neurons in Hibernating Mammalian Species
por: Horowitz, John M., et al.
Publicado: (2019)

Simple, biologically-constrained CA1 pyramidal cell models using an intact, whole hippocampus context
por: Ferguson, Katie A., et al.
Publicado: (2014)

Effects of Low Frequency Stimulation on Spontaneous Inhibitory and Excitatory Post-Synaptic Currents in Hippocampal CA1 Pyramidal Cells of Kindled Rats
por: Ghafouri, Samireh, et al.
Publicado: (2017)

Network mechanisms of theta related neuronal activity in hippocampal CA1 pyramidal neurons
por: Losonczy, Attila, et al.
Publicado: (2010)

Endocannabinoids Differentially Modulate Synaptic Plasticity in Rat Hippocampal CA1 Pyramidal Neurons
por: Xu, Jian-Yi, et al.
Publicado: (2010)

Somatosensory stimulation suppresses the excitability of pyramidal cells in the hippocampal CA1 region in rats
por: Wang, Yang, et al.
Publicado: (2014)

Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice
por: Tamagnini, Francesco, et al.
Publicado: (2015)

Coexistence of Multiple Types of Synaptic Plasticity in Individual Hippocampal CA1 Pyramidal Neurons
por: Edelmann, Elke, et al.
Publicado: (2017)

Excitability is increased in hippocampal CA1 pyramidal cells of Fmr1 knockout mice
por: Luque, M. Angeles, et al.
Publicado: (2017)

Metformin Enhances Excitatory Synaptic Transmission onto Hippocampal CA1 Pyramidal Neurons
por: Chen, Wen-Bing, et al.
Publicado: (2020)

The Molecular Basis for the Calcium-Dependent Slow Afterhyperpolarization in CA1 Hippocampal Pyramidal Neurons
por: Sahu, Giriraj, et al.
Publicado: (2021)

Heterogeneous CaMKII-Dependent Synaptic Compensations in CA1 Pyramidal Neurons From Acute Hippocampal Slices
por: Vergara, Pablo, et al.
Publicado: (2022)

A critical role for CaMKII in behavioral timescale synaptic plasticity in hippocampal CA1 pyramidal neurons
por: Xiao, Kuo, et al.
Publicado: (2023)

Ionic Mechanisms of Endogenous Bursting in CA3 Hippocampal Pyramidal Neurons: A Model Study
por: Xu, Jun, et al.
Publicado: (2008)

Assessing the role of IKCa channels in generating the sAHP of CA1 hippocampal pyramidal cells
por: Turner, Ray W., et al.
Publicado: (2016)

Plasticity-dependent, full detonation at hippocampal mossy fiber–CA3 pyramidal neuron synapses
por: Vyleta, Nicholas P, et al.
Publicado: (2016)

Extrasynaptic NMDA receptor dependent long-term potentiation of hippocampal CA1 pyramidal neurons
por: Yang, Qian, et al.
Publicado: (2017)

Oxytocin stimulates hippocampal neurogenesis via oxytocin receptor expressed in CA3 pyramidal neurons
por: Lin, Yu-Ting, et al.
Publicado: (2017)

Membrane electrical properties of mouse hippocampal CA1 pyramidal neurons during strong inputs
por: Bianchi, Daniela, et al.
Publicado: (2022)

Ripple‐related firing of identified deep CA1 pyramidal cells in chronic temporal lobe epilepsy in mice
por: Marchionni, Ivan, et al.
Publicado: (2019)

Mitochondrial Ca(2+) uptake by the MCU facilitates pyramidal neuron excitability and metabolism during action potential firing
por: Groten, Christopher J., et al.
Publicado: (2022)

Oxytocin-Modulated Ion Channel Ensemble Controls Depolarization, Integration and Burst Firing in CA2 Pyramidal Neurons
por: Liu, Jing-Jing, et al.
Publicado: (2022)

Serotonin-mediated modulation of Na(+)/K(+ )pump current in rat hippocampal CA1 pyramidal neurons
por: Zhang, Li Nan, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_r0cggsrc4esup5kfule8t8g1mn