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Lung microhaemorrhage drives oxidative/inflammatory damage in α(1)-antitrypsin deficiency

BACKGROUND: Animal models using intratracheal instillation show that elastase, unopposed by α(1)-antitrypsin (AAT), causes alveolar damage and haemorrhage associated with emphysematous changes. The aim of the present study was to characterise any relationship between alveolar haemorrhage and human A...

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Detalles Bibliográficos
Autores principales:	Saltini, Cesare, Mohammad, Naweed, Xin, Yan, Alvarado, Rodolfo, Ghio, Andrew J., Moneypenny, Craig G., Riva, Alberto, Fu, Dongtao, Flagg, Tammy, Saltini, Giovanni F.A., Arisi, Ivan, Fredenburg, Kristianna M., Zhang, Yang, Lascano, Jorge E., Brantly, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Respiratory Society 2023
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258718/ https://www.ncbi.nlm.nih.gov/pubmed/37313399 http://dx.doi.org/10.1183/23120541.00662-2022

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