Generation of sheep with defined FecB(B) and TBXT mutations and porcine blastocysts with KCNJ5(G151R/+) mutation using prime editing

BACKGROUND: Rewriting the genomes of living organisms has been a long-standing aim in the biological sciences. The revelation of the CRISPR/Cas9 technology has revolutionized the entire biological field. Since its emergence, this technology has been widely applied to induce gene knockouts, insertion...

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Detalles Bibliográficos
Autores principales: Zhou, Shiwei, Lenk, Laura Johanna, Gao, Yawei, Wang, Yuhui, Zhao, Xiaoe, Pan, Menghao, Huang, Shuhong, Sun, Kexin, Kalds, Peter, Luo, Qi, Lillico, Simon, Sonstegard, Tad, Scholl, Ute I., Ma, Baohua, Petersen, Bjoern, Chen, Yulin, Wang, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258939/
https://www.ncbi.nlm.nih.gov/pubmed/37308830
http://dx.doi.org/10.1186/s12864-023-09409-y

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