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Krüppel-like factor 10 modulates stem cell phenotypes of pancreatic adenocarcinoma by transcriptionally regulating notch receptors

BACKGROUND: Pancreatic adenocarcinoma (PDAC) is well known for its rapid distant metastasis and local destructive behavior. Loss of Krüppel-like factor 10 (KLF10) contributes to distant migration of PDAC. The role of KLF10 in modulating tumorigenesis and stem cell phenotypes of PDAC is unclear. METH...

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Detalles Bibliográficos
Autores principales:	Tsai, Yi-Chih, Cheng, Kung Hung, Jiang, Shih Sheng, Hawse, John R., Chuang, Shun En, Chen, Su Liang, Huang, Tze-Sing, Ch’ang, Hui-Ju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258947/ https://www.ncbi.nlm.nih.gov/pubmed/37308977 http://dx.doi.org/10.1186/s12929-023-00937-z

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