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Improved genetic prediction of the risk of knee osteoarthritis using the risk factor-based polygenic score

BACKGROUND: Polygenic risk score (PRS) analysis is used to predict disease risk. Although PRS has been shown to have great potential in improving clinical care, PRS accuracy assessment has been mainly focused on European ancestry. This study aimed to develop an accurate genetic risk score for knee o...

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Detalles Bibliográficos
Autores principales:	Morita, Yugo, Kamatani, Yoichiro, Ito, Hiromu, Ikegawa, Shiro, Kawaguchi, Takahisa, Kawaguchi, Shuji, Takahashi, Meiko, Terao, Chikashi, Ito, Shuji, Nishitani, Kohei, Nakamura, Shinichiro, Kuriyama, Shinichi, Tabara, Yasuharu, Matsuda, Fumihiko, Matsuda, Shuichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258963/ https://www.ncbi.nlm.nih.gov/pubmed/37309008 http://dx.doi.org/10.1186/s13075-023-03082-y

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