Cargando…
Mass cytometric analysis of the immune cell landscape after traumatic brain injury elucidates the role of complement and complement receptors in neurologic outcomes
Following traumatic brain injury (TBI), a neuroinflammatory response can persist for years and contribute to the development of chronic neurological manifestations. Complement plays a central role in post-TBI neuroinflammation, and C3 opsonins and the anaphylatoxins (C3a and C5a) have been implicate...
Autores principales: | Toutonji, Amer, Krieg, Carsten, Borucki, Davis M., Mandava, Mamatha, Guglietta, Silvia, Tomlinson, Stephen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258994/ https://www.ncbi.nlm.nih.gov/pubmed/37308987 http://dx.doi.org/10.1186/s40478-023-01583-0 |
Ejemplares similares
-
Chronic complement dysregulation drives neuroinflammation after traumatic brain injury: a transcriptomic study
por: Toutonji, Amer, et al.
Publicado: (2021) -
Complement-Mediated Microglial Phagocytosis and Pathological Changes in the Development and Degeneration of the Visual System
por: Borucki, Davis M., et al.
Publicado: (2020) -
A Role for P-selectin and Complement in the Pathological Sequelae of Germinal Matrix Hemorrhage
por: Hatchell, Devin, et al.
Publicado: (2023) -
A role for P-selectin and complement in the pathological sequelae of germinal matrix hemorrhage
por: Hatchell, Devin, et al.
Publicado: (2023) -
Evaluating the comorbidities of age and cigarette smoking on stroke outcomes in the context of anti-complement mitigation strategies
por: Couch, Christine, et al.
Publicado: (2023)