Varicella-zoster virus proteome-wide T-cell screening demonstrates low prevalence of virus-specific CD8 T-cells in latently infected human trigeminal ganglia

BACKGROUND: Trigeminal ganglia (TG) neurons are an important site of lifelong latent varicella-zoster virus (VZV) infection. Although VZV-specific T-cells are considered pivotal to control virus reactivation, their protective role at the site of latency remains uncharacterized. METHODS: Paired blood...

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Detalles Bibliográficos
Autores principales: van Gent, Michiel, Ouwendijk, Werner J. D., Campbell, Victoria L., Laing, Kerry J., Verjans, Georges M. G. M., Koelle, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259006/
https://www.ncbi.nlm.nih.gov/pubmed/37308917
http://dx.doi.org/10.1186/s12974-023-02820-y

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