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Procedure-related pain during CT-guided percutaneous transthoracic needle biopsies of lung lesions: a prospective study
BACKGROUND: The existing data on the degree of pain in patients during CT-guided percutaneous transthoracic needle biopsy (PTNB) of lung lesions are limited and the factors related to pain are unclear. In this study, we aimed to evaluate the prevalence and severity of pain reported during PTNB and t...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259012/ https://www.ncbi.nlm.nih.gov/pubmed/37308928 http://dx.doi.org/10.1186/s40644-023-00578-3 |
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author | Yang, Shou-Xin Chen, Mai-Lin Xie, Lei Zhu, Hai-Bin Liu, Yu-Liang Sun, Rui-Jia Zhao, Bo Deng, Xu-Bo Li, Xiao-Ting Sun, Ying-Shi |
author_facet | Yang, Shou-Xin Chen, Mai-Lin Xie, Lei Zhu, Hai-Bin Liu, Yu-Liang Sun, Rui-Jia Zhao, Bo Deng, Xu-Bo Li, Xiao-Ting Sun, Ying-Shi |
author_sort | Yang, Shou-Xin |
collection | PubMed |
description | BACKGROUND: The existing data on the degree of pain in patients during CT-guided percutaneous transthoracic needle biopsy (PTNB) of lung lesions are limited and the factors related to pain are unclear. In this study, we aimed to evaluate the prevalence and severity of pain reported during PTNB and to identify factors associated with increased reported pain. METHODS: Patients who underwent PTNB from April 2022 to November 2022 were prospectively evaluated using the numeric rating scale, which assesses subjective pain based on a 0–10 scoring system (0 = no pain; 10 = the worst pain imaginable). The scale divides the scores into three categories: mild pain (1–3 points), moderate pain (4–6 points), and severe pain (7–10 points). Pain scores from 4 to 10 were considered significant pain. Demographic data of patients, lesion characteristics, biopsy variables, complications, the patient’s subjective feelings, and pathological result data were analyzed by multivariable logistic regression analysis to identify variables associated with significant pain. RESULTS: We enrolled 215 participants who underwent 215 biopsy procedures (mean age: 64.5 ± 9.3 years, 123 were men). The mean procedure-related pain score was 2 ± 2. Overall, 20% (43/215) of participants reported no pain (score of 0), 67.9% (146/215) reported pain scores of 1–3, 11.2% (24/215) reported scores of 4–6, and 0.9% (2/215) reported scores of 7 or higher. Furthermore, non-significant pain (scores of 0–3) was reported during 87.9% (189/215) of the procedures. In the adjusted model, significant pain was positively associated with lesions ≥ 34 mm (p = 0.001, odds ratio [OR] = 6.90; 95% confidence interval [CI]: 2.18, 21.85), a needle-pleural angle ≥ 77° (p = 0.047, OR = 2.44; 95% CI: 1.01, 5.89), and a procedure time ≥ 26.5 min (p = 0.031, OR = 3.11; 95% CI: 1.11, 8.73). CONCLUSIONS: Most participants reported no pain or mild pain from CT-guided percutaneous transthoracic needle biopsies of lung lesions. However, those with a larger lesion, a greater needle-pleural angle, and a longer procedure time reported greater pain. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40644-023-00578-3. |
format | Online Article Text |
id | pubmed-10259012 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-102590122023-06-13 Procedure-related pain during CT-guided percutaneous transthoracic needle biopsies of lung lesions: a prospective study Yang, Shou-Xin Chen, Mai-Lin Xie, Lei Zhu, Hai-Bin Liu, Yu-Liang Sun, Rui-Jia Zhao, Bo Deng, Xu-Bo Li, Xiao-Ting Sun, Ying-Shi Cancer Imaging Research Article BACKGROUND: The existing data on the degree of pain in patients during CT-guided percutaneous transthoracic needle biopsy (PTNB) of lung lesions are limited and the factors related to pain are unclear. In this study, we aimed to evaluate the prevalence and severity of pain reported during PTNB and to identify factors associated with increased reported pain. METHODS: Patients who underwent PTNB from April 2022 to November 2022 were prospectively evaluated using the numeric rating scale, which assesses subjective pain based on a 0–10 scoring system (0 = no pain; 10 = the worst pain imaginable). The scale divides the scores into three categories: mild pain (1–3 points), moderate pain (4–6 points), and severe pain (7–10 points). Pain scores from 4 to 10 were considered significant pain. Demographic data of patients, lesion characteristics, biopsy variables, complications, the patient’s subjective feelings, and pathological result data were analyzed by multivariable logistic regression analysis to identify variables associated with significant pain. RESULTS: We enrolled 215 participants who underwent 215 biopsy procedures (mean age: 64.5 ± 9.3 years, 123 were men). The mean procedure-related pain score was 2 ± 2. Overall, 20% (43/215) of participants reported no pain (score of 0), 67.9% (146/215) reported pain scores of 1–3, 11.2% (24/215) reported scores of 4–6, and 0.9% (2/215) reported scores of 7 or higher. Furthermore, non-significant pain (scores of 0–3) was reported during 87.9% (189/215) of the procedures. In the adjusted model, significant pain was positively associated with lesions ≥ 34 mm (p = 0.001, odds ratio [OR] = 6.90; 95% confidence interval [CI]: 2.18, 21.85), a needle-pleural angle ≥ 77° (p = 0.047, OR = 2.44; 95% CI: 1.01, 5.89), and a procedure time ≥ 26.5 min (p = 0.031, OR = 3.11; 95% CI: 1.11, 8.73). CONCLUSIONS: Most participants reported no pain or mild pain from CT-guided percutaneous transthoracic needle biopsies of lung lesions. However, those with a larger lesion, a greater needle-pleural angle, and a longer procedure time reported greater pain. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40644-023-00578-3. BioMed Central 2023-06-12 /pmc/articles/PMC10259012/ /pubmed/37308928 http://dx.doi.org/10.1186/s40644-023-00578-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Yang, Shou-Xin Chen, Mai-Lin Xie, Lei Zhu, Hai-Bin Liu, Yu-Liang Sun, Rui-Jia Zhao, Bo Deng, Xu-Bo Li, Xiao-Ting Sun, Ying-Shi Procedure-related pain during CT-guided percutaneous transthoracic needle biopsies of lung lesions: a prospective study |
title | Procedure-related pain during CT-guided percutaneous transthoracic needle biopsies of lung lesions: a prospective study |
title_full | Procedure-related pain during CT-guided percutaneous transthoracic needle biopsies of lung lesions: a prospective study |
title_fullStr | Procedure-related pain during CT-guided percutaneous transthoracic needle biopsies of lung lesions: a prospective study |
title_full_unstemmed | Procedure-related pain during CT-guided percutaneous transthoracic needle biopsies of lung lesions: a prospective study |
title_short | Procedure-related pain during CT-guided percutaneous transthoracic needle biopsies of lung lesions: a prospective study |
title_sort | procedure-related pain during ct-guided percutaneous transthoracic needle biopsies of lung lesions: a prospective study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259012/ https://www.ncbi.nlm.nih.gov/pubmed/37308928 http://dx.doi.org/10.1186/s40644-023-00578-3 |
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