RGS14 limits seizure-induced mitochondrial oxidative stress and pathology in hippocampus

RGS14 is a complex multifunctional scaffolding protein that is highly enriched within pyramidal cells (PCs) of hippocampal area CA2. In these neurons, RGS14 suppresses glutamate-induced calcium influx and related G protein and ERK signaling in dendritic spines to restrain postsynaptic signaling and...

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Detalles Bibliográficos
Autores principales: Harbin, N.H., Lustberg, D.J., Hurst, C., Pare, J., Crotty, K.M., Waters, A.L., Yeligar, S.M., Smith, Y., Seyfried, N.T., Weinshenker, D., Hepler, J.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259180/
https://www.ncbi.nlm.nih.gov/pubmed/37075948
http://dx.doi.org/10.1016/j.nbd.2023.106128

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