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Chronologically modified androgen receptor in recurrent castration-resistant prostate cancer and its therapeutic targeting
Resistance to second-generation androgen receptor (AR) antagonists such as enzalutamide is an inevitable consequence in patients with castration-resistant prostate cancer (CRPC). There are no effective therapeutic options for this recurrent disease. The expression of truncated AR variant 7 (AR-V7) h...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259236/ https://www.ncbi.nlm.nih.gov/pubmed/35704598 http://dx.doi.org/10.1126/scitranslmed.abg4132 |