Catalytic domain-dependent and -independent transcriptional activities of the tumour suppressor histone H3K27 demethylase UTX/KDM6A in specific cancer types

The histone H3K27 demethylase, UTX/KDM6A, plays a critical role in the early development of vertebrates, and mutations are frequently found in various cancers. Several studies on developmental and cancer biology have focused on preferential transcriptional regulation by UTX independently of its H3K2...

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Detalles Bibliográficos
Autores principales: Sun, Wendi, Lee, Kian Leong, Poellinger, Lorenz, Masai, Hisao, Kato, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259304/
https://www.ncbi.nlm.nih.gov/pubmed/37300822
http://dx.doi.org/10.1080/15592294.2023.2222245

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