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SAKK 21/12: a phase II trial of transdermal CR1447 in breast cancer patients

OBJECTIVE: CR1447, a novel transdermal formulation of 4-hydroxytestosterone, has aromatase-inhibiting and androgen receptor (AR)-modulating properties (IC(50)4.4 nM) with antitumor effects against AR-positive tumor cells in vitro. This trial investigated the efficacy and safety of CR1447 for patient...

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Detalles Bibliográficos
Autores principales:	Vetter, Marcus, Rothgiesser, Karin M, Li, Qiyu, Hawle, Hanne, Schönfeld, Wolfgang, Ribi, Karin, Riniker, Salome, von Moos, Roger, Trojan, Andreas, Kralidis, Elena, Fehr, Mathias, Müller, Andreas, Thürlimann, Beat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259314/ https://www.ncbi.nlm.nih.gov/pubmed/37435469 http://dx.doi.org/10.1530/EO-21-0009

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