The paralogues MAGOH and MAGOHB are oncogenic factors in high-grade gliomas and safeguard the splicing of cell division and cell cycle genes

The exon junction complex (EJC) plays key roles throughout the lifespan of RNA and is particularly relevant in the nervous system. We investigated the roles of two EJC members, the paralogs MAGOH and MAGOHB, with respect to brain tumour development. High MAGOH/MAGOHB expression was observed in 14 tu...

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Detalles Bibliográficos
Autores principales: Barreiro, Rodrigo A. S., Guardia, Gabriela D. A., Meliso, Fabiana M., Lei, Xiufen, Li, Wei-Qing, Savio, Andre, Fellermeyer, Martin, Conceição, Helena B., Mercuri, Rafael L. V., Landry, Tesha, Qiao, Mei, Blazquez, Lorea, Ule, Jernej, Penalva, Luiz O.F., Galante, Pedro A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259345/
https://www.ncbi.nlm.nih.gov/pubmed/37294214
http://dx.doi.org/10.1080/15476286.2023.2221511

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