Molecular mechanisms involved in somatostatin receptor regulation in corticotroph tumors: the role of cytoskeleton and USP8 mutations

Adrenocorticotropic hormone (ACTH)-secreting pituitary tumors mainly express somatostatin receptor 5 (SSTR5) since SSTR2 is downregulated by the elevated levels of glucocorticoids that characterize patients with Cushing’s disease (CD). SSTR5 is the molecular target of pasireotide, the only approved...

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Detalles Bibliográficos
Autores principales: Peverelli, Erika, Treppiedi, Donatella, Mantovani, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259348/
https://www.ncbi.nlm.nih.gov/pubmed/37435448
http://dx.doi.org/10.1530/EO-22-0042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259348/
https://www.ncbi.nlm.nih.gov/pubmed/37435448
http://dx.doi.org/10.1530/EO-22-0042

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