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Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin

Bullous hemorrhagic dermatosis is a rare cutaneous reaction of heparin, a commonly used anticoagulant. Exact etiopathogenesis remains elusive but immune related mechanisms as well as dose dependent relationship have been proposed. Clinically, it is characterized by asymptomatic, tense hemorrhagic bu...

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Detalles Bibliográficos
Autores principales: Dhattarwal, N, Gurjar, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259437/
https://www.ncbi.nlm.nih.gov/pubmed/36861545
http://dx.doi.org/10.4103/jpgm.jpgm_282_22
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author Dhattarwal, N
Gurjar, R
author_facet Dhattarwal, N
Gurjar, R
author_sort Dhattarwal, N
collection PubMed
description Bullous hemorrhagic dermatosis is a rare cutaneous reaction of heparin, a commonly used anticoagulant. Exact etiopathogenesis remains elusive but immune related mechanisms as well as dose dependent relationship have been proposed. Clinically, it is characterized by asymptomatic, tense hemorrhagic bullae on extremities or abdomen occurring 5-21 days after initiation of therapy. We report bilateral symmetrically grouped lesions, in a previously unreported distribution of this entity in both the forearms in a 50-year-old male admitted with acute coronary syndrome on oral ecosprin, oral clopidogrel and subcutaneous enoxaparin. The condition is self-resolving and discontinuation of drug is not required.
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spelling pubmed-102594372023-06-13 Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin Dhattarwal, N Gurjar, R J Postgrad Med ADR Report Bullous hemorrhagic dermatosis is a rare cutaneous reaction of heparin, a commonly used anticoagulant. Exact etiopathogenesis remains elusive but immune related mechanisms as well as dose dependent relationship have been proposed. Clinically, it is characterized by asymptomatic, tense hemorrhagic bullae on extremities or abdomen occurring 5-21 days after initiation of therapy. We report bilateral symmetrically grouped lesions, in a previously unreported distribution of this entity in both the forearms in a 50-year-old male admitted with acute coronary syndrome on oral ecosprin, oral clopidogrel and subcutaneous enoxaparin. The condition is self-resolving and discontinuation of drug is not required. Wolters Kluwer - Medknow 2023 2023-02-23 /pmc/articles/PMC10259437/ /pubmed/36861545 http://dx.doi.org/10.4103/jpgm.jpgm_282_22 Text en Copyright: © 2023 Journal of Postgraduate Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle ADR Report
Dhattarwal, N
Gurjar, R
Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin
title Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin
title_full Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin
title_fullStr Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin
title_full_unstemmed Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin
title_short Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin
title_sort bullous hemorrhagic dermatosis: a rare cutaneous reaction of heparin
topic ADR Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259437/
https://www.ncbi.nlm.nih.gov/pubmed/36861545
http://dx.doi.org/10.4103/jpgm.jpgm_282_22
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