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Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin
Bullous hemorrhagic dermatosis is a rare cutaneous reaction of heparin, a commonly used anticoagulant. Exact etiopathogenesis remains elusive but immune related mechanisms as well as dose dependent relationship have been proposed. Clinically, it is characterized by asymptomatic, tense hemorrhagic bu...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259437/ https://www.ncbi.nlm.nih.gov/pubmed/36861545 http://dx.doi.org/10.4103/jpgm.jpgm_282_22 |
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author | Dhattarwal, N Gurjar, R |
author_facet | Dhattarwal, N Gurjar, R |
author_sort | Dhattarwal, N |
collection | PubMed |
description | Bullous hemorrhagic dermatosis is a rare cutaneous reaction of heparin, a commonly used anticoagulant. Exact etiopathogenesis remains elusive but immune related mechanisms as well as dose dependent relationship have been proposed. Clinically, it is characterized by asymptomatic, tense hemorrhagic bullae on extremities or abdomen occurring 5-21 days after initiation of therapy. We report bilateral symmetrically grouped lesions, in a previously unreported distribution of this entity in both the forearms in a 50-year-old male admitted with acute coronary syndrome on oral ecosprin, oral clopidogrel and subcutaneous enoxaparin. The condition is self-resolving and discontinuation of drug is not required. |
format | Online Article Text |
id | pubmed-10259437 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-102594372023-06-13 Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin Dhattarwal, N Gurjar, R J Postgrad Med ADR Report Bullous hemorrhagic dermatosis is a rare cutaneous reaction of heparin, a commonly used anticoagulant. Exact etiopathogenesis remains elusive but immune related mechanisms as well as dose dependent relationship have been proposed. Clinically, it is characterized by asymptomatic, tense hemorrhagic bullae on extremities or abdomen occurring 5-21 days after initiation of therapy. We report bilateral symmetrically grouped lesions, in a previously unreported distribution of this entity in both the forearms in a 50-year-old male admitted with acute coronary syndrome on oral ecosprin, oral clopidogrel and subcutaneous enoxaparin. The condition is self-resolving and discontinuation of drug is not required. Wolters Kluwer - Medknow 2023 2023-02-23 /pmc/articles/PMC10259437/ /pubmed/36861545 http://dx.doi.org/10.4103/jpgm.jpgm_282_22 Text en Copyright: © 2023 Journal of Postgraduate Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | ADR Report Dhattarwal, N Gurjar, R Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin |
title | Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin |
title_full | Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin |
title_fullStr | Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin |
title_full_unstemmed | Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin |
title_short | Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin |
title_sort | bullous hemorrhagic dermatosis: a rare cutaneous reaction of heparin |
topic | ADR Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259437/ https://www.ncbi.nlm.nih.gov/pubmed/36861545 http://dx.doi.org/10.4103/jpgm.jpgm_282_22 |
work_keys_str_mv | AT dhattarwaln bulloushemorrhagicdermatosisararecutaneousreactionofheparin AT gurjarr bulloushemorrhagicdermatosisararecutaneousreactionofheparin |