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Multi-centre analysis of networks and genes modulated by hypothalamic stimulation in patients with aggressive behaviours

Deep brain stimulation targeting the posterior hypothalamus (pHyp-DBS) is being investigated as a treatment for refractory aggressive behavior, but its mechanisms of action remain elusive. We conducted an integrated imaging analysis of a large multi-centre dataset, incorporating volume of activated...

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Detalles Bibliográficos
Autores principales: Gouveia, Flavia Venetucci, Germann, Jurgen, Elias, Gavin JB, Boutet, Alexandre, Loh, Aaron, Lopez Rios, Adriana Lucia, Torres Diaz, Cristina, Contreras Lopez, William Omar, Martinez, Raquel Chacon Ruiz, Fonoff, Erich Talamoni, Benedetti-Isaac, Juan Carlos, Giacobbe, Peter, Arango Pava, Pablo M, Yan, Han, Ibrahim, George M, Lipsman, Nir, Lozano, Andres, Hamani, Clement
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259501/
https://www.ncbi.nlm.nih.gov/pubmed/37212456
http://dx.doi.org/10.7554/eLife.84566

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