Cargando…
Sex-related differences in retinal function in Wistar rats: implications for toxicity and safety studies
Introduction: Wistar Han rats are a preferred strain of rodents for general toxicology and safety pharmacology studies in drug development. In some of these studies, visual functional tests that assess for retinal toxicity are included as an additional endpoint. Although the influence of gender on h...
Autores principales: | Tyszkiewicz, Cheryl, Hwang, Seo-Kyoung, Manickam, Balasubramanian, Jakubczak, Ben, Walters, Karen M., Bolt, Michael W., Santos, Rosemary, Liu, Chang-Ning |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259507/ https://www.ncbi.nlm.nih.gov/pubmed/37313214 http://dx.doi.org/10.3389/ftox.2023.1176665 |
Ejemplares similares
-
Skeletal effects following developmental flame-retardant exposure are specific to sex and chemical class in the adult Wistar rat
por: Schkoda, Stacy, et al.
Publicado: (2023) -
Safety and Toxicity Implications of Multifunctional Drug Delivery Nanocarriers on Reproductive Systems In Vitro and In Vivo
por: Ahmad, Anas
Publicado: (2022) -
Translating Neurobehavioral Toxicity Across Species From Zebrafish to Rats to Humans: Implications for Risk Assessment
por: Vorhees, Charles V., et al.
Publicado: (2021) -
Flavoured water consumption alters pharmacokinetic parameters and increases exposure of erlotinib and gefitinib in a preclinical study using Wistar rats
por: Almomen, Aliyah, et al.
Publicado: (2020) -
Strain differences in cytochrome P450 mRNA and protein expression, and
enzymatic activity among Sprague Dawley, Wistar, Brown Norway and Dark Agouti
rats
por: NISHIYAMA, Yoshihiro, et al.
Publicado: (2016)