The αTSR Domain of Plasmodium Circumsporozoite Protein Bound Heparan Sulfates and Elicited High Titers of Sporozoite Binding Antibody After Displayed by Nanoparticles

INTRODUCTION: Malaria is a devastating infectious illness caused by protozoan Plasmodium parasites. The circumsporozoite protein (CSP) on Plasmodium sporozoites binds heparan sulfate proteoglycan (HSPG) receptors for liver invasion, a critical step for prophylactic and therapeutic interventions. MET...

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Detalles Bibliográficos
Autores principales: Xia, Ming, Vago, Frank, Han, Ling, Huang, Pengwei, Nguyen, Linh, Boons, Geert-Jan, Klassen, John S, Jiang, Wen, Tan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259582/
https://www.ncbi.nlm.nih.gov/pubmed/37312932
http://dx.doi.org/10.2147/IJN.S406314

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