Characterization of a Novel Gja8 (Cx50) Mutation in a New Cataract Rat Model

PURPOSE: To describe a novel spontaneous cataract inbred strain isolated from large-scale breeding SD rats, identify the responsible gene mutation, and understand how this mutation affects lens function. METHODS: Exome sequencing of 12 cataract-associated genes was performed in the affected and heal...

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Detalles Bibliográficos
Autores principales: Shen, Jiawei, Wu, Qiuyue, You, Jinwei, Zhang, Xiaoran, Zhu, Lei, Xia, Xinyi, Xue, Chunyan, Tian, Xiaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Lens
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259676/
https://www.ncbi.nlm.nih.gov/pubmed/37294706
http://dx.doi.org/10.1167/iovs.64.7.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259676/
https://www.ncbi.nlm.nih.gov/pubmed/37294706
http://dx.doi.org/10.1167/iovs.64.7.18

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