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Bixin and Fuxoxanthin Alone and in Combination with Cisplatin Regulate ABCC1 and ABCC2 Transcription in A549 Lung Cancer Cells

BACKGROUND: The ATP-Binding Cassette (ABC) transporter has long been studied to confer drug resistance in human tumors and play important role in metabolic processes and cellular signaling. The overexpression of ABCB1, ABCC1, ABCC2, ABCC3, and ABCG2 leads to decreased sensitivity of lung cancer to c...

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Detalles Bibliográficos
Autores principales: Chandra, Ferdy, Tania, Teresa F., Nurcahyanti, Agustina D. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259734/
https://www.ncbi.nlm.nih.gov/pubmed/37313537
http://dx.doi.org/10.4103/jpbs.jpbs_50_23