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Neuromyelitis Optica: A Case Report From a Radiological Perspective

Neuromyelitis optica (NMO), also known as Devic’s disease, is a chronic inflammatory disorder of the optic nerve and the spinal cord. Similar to multiple sclerosis, it has a relapsing and remitting characteristic. The disease is characterized by optic neuritis and longitudinal extensive inflammation...

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Autores principales: Rentiya, Zubir S, Akuma, Ogbonnaya, Haseeb, Madiha, Okonkwo, Chinwe C, Khan, Dr. Aadil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259745/
https://www.ncbi.nlm.nih.gov/pubmed/37313063
http://dx.doi.org/10.7759/cureus.38945
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author Rentiya, Zubir S
Akuma, Ogbonnaya
Haseeb, Madiha
Okonkwo, Chinwe C
Khan, Dr. Aadil
author_facet Rentiya, Zubir S
Akuma, Ogbonnaya
Haseeb, Madiha
Okonkwo, Chinwe C
Khan, Dr. Aadil
author_sort Rentiya, Zubir S
collection PubMed
description Neuromyelitis optica (NMO), also known as Devic’s disease, is a chronic inflammatory disorder of the optic nerve and the spinal cord. Similar to multiple sclerosis, it has a relapsing and remitting characteristic. The disease is characterized by optic neuritis and longitudinal extensive inflammation of the spinal cord. Magnetic resonance imaging (MRI) is the modality of choice for this disorder. The serological examination also shows the presence of aquaporin-4 (AQP4) autoantibodies. MRI shows longitudinal extensive transverse myelitis and signs of optic neuritis such as inflammation of the optic nerve. The treatment is based on intravenous corticosteroids with or without plasmapheresis. The current case is a 25-year-old African American male patient who presented with multiple sclerosis-like symptoms (i.e., optic neuritis and transverse myelitis) but turned out to have NMO. Serological examination reveals the absence of AQP4 autoantibodies. A radiological examination showed swelling in the cervical cord. This case report strongly focuses on the radiological findings of NMO.
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spelling pubmed-102597452023-06-13 Neuromyelitis Optica: A Case Report From a Radiological Perspective Rentiya, Zubir S Akuma, Ogbonnaya Haseeb, Madiha Okonkwo, Chinwe C Khan, Dr. Aadil Cureus Internal Medicine Neuromyelitis optica (NMO), also known as Devic’s disease, is a chronic inflammatory disorder of the optic nerve and the spinal cord. Similar to multiple sclerosis, it has a relapsing and remitting characteristic. The disease is characterized by optic neuritis and longitudinal extensive inflammation of the spinal cord. Magnetic resonance imaging (MRI) is the modality of choice for this disorder. The serological examination also shows the presence of aquaporin-4 (AQP4) autoantibodies. MRI shows longitudinal extensive transverse myelitis and signs of optic neuritis such as inflammation of the optic nerve. The treatment is based on intravenous corticosteroids with or without plasmapheresis. The current case is a 25-year-old African American male patient who presented with multiple sclerosis-like symptoms (i.e., optic neuritis and transverse myelitis) but turned out to have NMO. Serological examination reveals the absence of AQP4 autoantibodies. A radiological examination showed swelling in the cervical cord. This case report strongly focuses on the radiological findings of NMO. Cureus 2023-05-12 /pmc/articles/PMC10259745/ /pubmed/37313063 http://dx.doi.org/10.7759/cureus.38945 Text en Copyright © 2023, Rentiya et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Rentiya, Zubir S
Akuma, Ogbonnaya
Haseeb, Madiha
Okonkwo, Chinwe C
Khan, Dr. Aadil
Neuromyelitis Optica: A Case Report From a Radiological Perspective
title Neuromyelitis Optica: A Case Report From a Radiological Perspective
title_full Neuromyelitis Optica: A Case Report From a Radiological Perspective
title_fullStr Neuromyelitis Optica: A Case Report From a Radiological Perspective
title_full_unstemmed Neuromyelitis Optica: A Case Report From a Radiological Perspective
title_short Neuromyelitis Optica: A Case Report From a Radiological Perspective
title_sort neuromyelitis optica: a case report from a radiological perspective
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259745/
https://www.ncbi.nlm.nih.gov/pubmed/37313063
http://dx.doi.org/10.7759/cureus.38945
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