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The order of sequential exposure of U2OS cells to gamma and alpha radiation influences the formation and decay dynamics of NBS1 foci

DNA double strand breaks (DSBs) are a deleterious form of DNA damage. Densely ionising alpha radiation predominantly induces complex DSBs and sparsely ionising gamma radiation—simple DSBs. We have shown that alphas and gammas, when applied simultaneously, interact in producing a higher DNA damage re...

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Detalles Bibliográficos
Autores principales: Tartas, Adrianna, Lundholm, Lovisa, Scherthan, Harry, Wojcik, Andrzej, Brzozowska, Beata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259794/
https://www.ncbi.nlm.nih.gov/pubmed/37307266
http://dx.doi.org/10.1371/journal.pone.0286902

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