A monoclonal antibody raised against human EZH2 cross-reacts with the RNA-binding protein SAFB

The Polycomb Repressive Complex 2 (PRC2) is a conserved enzyme that tri-methylates Lysine 27 on Histone 3 (H3K27me3) to promote gene silencing. PRC2 is remarkably responsive to the expression of certain long noncoding RNAs (lncRNAs). In the most notable example, PRC2 is recruited to the X-chromosome...

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Detalles Bibliográficos
Autores principales: Cherney, Rachel E., Mills, Christine A., Herring, Laura E., Braceros, Aki K., Calabrese, J. Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Methods & Techniques
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259849/
https://www.ncbi.nlm.nih.gov/pubmed/37283223
http://dx.doi.org/10.1242/bio.059955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259849/
https://www.ncbi.nlm.nih.gov/pubmed/37283223
http://dx.doi.org/10.1242/bio.059955

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