RARE-03. GENOME-WIDE ASSOCIATION STUDY OF INTRACRANIAL GERM CELL TUMORS: A COMMON DELETION AT BAK1 ATTENUATES THE ENHANCER ACTIVITY AND CONFERS RISK FOR THE BRAIN TUMORS IN CHILDREN ADOLESCENTS AND YOUNG ADULTS

Intracranial germ cell tumors (IGCTs) are rare brain tumors that mainly occur in children, adolescents and young adults with a particularly high incidence in East Asian populations. The biological basis of these tumors is still largely unknown. We conduct a genome-wide association study (GWAS) of 13...

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Detalles Bibliográficos
Autores principales: Terashima, Keita, Sonehara, Kyuto, Kimura, Yui, Nakano, Yoshiko, Ozawa, Tatsuya, Takahashi, Meiko, Suzuki, Kenji, Fujii, Takashi, Matsuhita, Yuko, Tomiyama, Arata, Kishikawa, Toshihiro, Yamamoto, Kenichi, Naito, Tatsuhiko, Suzuki, Tomonori, Yamaguchi, Shigeru, Miwa, Tomoru, Sasaki, Hikaru, Kitagawa, Masashi, Ohe, Naoyuki, Fukai, Junya, Ogiwara, Hideki, Kawamura, Atsufumi, Miyawaki, Satoru, Matsuda, Fumihiko, Kiyokawa, Nobutaka, Ichimura, Koichi, Nishikawa, Ryo, Okada, Yukinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Germ Cell Tumors/Rare Tumors - RARE
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259888/
http://dx.doi.org/10.1093/neuonc/noad073.132

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