BIOL-14. FROM NON-MALIGNANT TO MALIGNANT: GENERATING AND TARGETING DIFFUSE MIDLINE GLIOMA IN A NOVEL HUMAN PONTINE ORGANOID MODEL

Diffuse Midline Glioma (DMG) is a rare and aggressive pediatric cancer with no chance of survival, demonstrating a critical need for therapy development. Predictive preclinical models that take into account the unique developmental background and anatomical environment of DMG, are so far lacking. We...

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Detalles Bibliográficos
Autores principales: Bessler, Nils, Moreno, Cristian Ruiz, Wezenaar, Amber, Dommann, Noëlle, Keramati, Farid, Ariese, Hendrikus C R, Honhoff, Celina, de Blank, Sam, Román, Mario Barrera, Collot, Raphaël, van Ineveld, Ravian, Krashennikova, Maria Alieva, Kranendonk, Mariette E G, Wehrens, Ellen J, Alemany, Anna, Stunnenberg, Henk G, Rios, Anne C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Basic Biology/Stem Cells/Models - BIOL
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259896/
http://dx.doi.org/10.1093/neuonc/noad073.033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259896/
http://dx.doi.org/10.1093/neuonc/noad073.033

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