LGG-07. TARGETED THERAPY IN PEDIATRIC LOW-GRADE GLIOMAS; REAL WORLD DATA IN THE CONTEXT OF CONVENTIONAL TREATMENT MODALITIES

Progressive inoperable pediatric low-grade gliomas (pLGG) are challenging and chemotherapy provides unsatisfactory long-term disease control. Majority of pLGGs harbor oncogenic MAPK pathway alterations. BRAF and MEK inhibitors were developed and available data suggest possible benefit in pLGG patien...

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Detalles Bibliográficos
Autores principales: Sumerauer, David, Trkova, Katerina, Koblizek, Miroslav, Kyncl, Martin, Krskova, Lenka, Benes, Vladimir, Zapotocky, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Low Grade Gliomas - LGG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259912/
http://dx.doi.org/10.1093/neuonc/noad073.217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259912/
http://dx.doi.org/10.1093/neuonc/noad073.217

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