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EPEN-11. CHARACTERIZATION OF THE SPATIAL ARCHITECTURE OF INTRATUMORAL CELL STATES IN PEDIATRIC HIGH-RISK EPENDYMOMA
By single-cell analyses, we previously uncovered distinct intratumoral transcriptomic ependymoma (EPN) cell states and developmental trajectories correlating with molecular subtype and biological behavior. However, the relation of these cell states to characteristic EPN tissue architecture and tumor...
Autores principales: | Bruckner, Katharina, Madlener, Sibylle, Biagi Junior, Carlos A O, Gabler, Lisa, Senfter, Daniel, Jeong, Daeun, Jiang, Li, Englinger, Bernhard, Jaunecker, Carola, Bilban, Martin, Haberler, Christine, Dorfer, Christian, Rössler, Karl, Kool, Marcel, Berger, Walter, Filbin, Mariella G, Lötsch-Gojo, Daniela, Gojo, Johannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259916/ http://dx.doi.org/10.1093/neuonc/noad073.115 |
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