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MDB-14. MULTI-OMICS OF HUMAN MEDULLOBLASTOMAS AND GENETIC LINEAGE TRACING IN VIVO IDENTIFY REGULATORS OF STEM-CELL MAINTENANCE

Recent studies implicate the glutamatergic lineage of the rhombic lip (RL) as the origin of group 3/4 medulloblastomas (MBs). MB stem cells resemble stalled RL progenitors and targeting common pluripotency factors induces differentiated phenotypes. However, the genetic and epigenetic regulators of s...

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Detalles Bibliográficos
Autores principales:	Yu, Bohyeon, Jung, Jangham, Hoare, Owen, Shamardani, Karin, Diaz, Aaron
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Final Category: Medulloblastomas - MDB
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259919/ http://dx.doi.org/10.1093/neuonc/noad073.247

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