MDB-45. SELECTIVE B7-H3 INHIBITORS NI1 AND NI4 REDUCE AGGRESSIVENESS OF GROUP 3 MEDULLOBLASTOMA

Medulloblastoma (MB) is a primary childhood malignancy of the central nervous system (CNS). Clinically heterogenous MB are sub-grouped into four molecular subgroups, i.e. Wingless (WNT), Sonic Hedgehog (SHH), Group 3, and Group 4. Among all, Group 3 MB (G3MB) is known to be the most aggressive form,...

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Detalles Bibliográficos
Autores principales: Krishnan, Prakadeeswari Gopala, Kanchan, Ranjana, Doss, David, Alfrefaei, Hamdan, Agarwal, Prachi, Chhonker, Yashpal, Murry, D J J, Trippier, Paul, Mahapatra, Sidharth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Medulloblastomas - MDB
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259933/
http://dx.doi.org/10.1093/neuonc/noad073.277

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