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METB-01. EXTRACHROMOSOMAL DNA IS ASSOCIATED WITH ONCOGENE AMPLIFICATION AND POOR SURVIVAL ACROSS MULTIPLE PEDIATRIC CANCER TYPES

Circular extrachromosomal DNA (ecDNA) is an important driver of aggressive cancers. Its frequency and impact on the spectrum of pediatric cancers has yet to be fully described. To determine the ecDNA prevalence in various pediatric cancer types, we accessed whole genome sequencing (WGS) data in the...

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Detalles Bibliográficos
Autores principales:	Sridhar, Sunita, Chapman, Owen, Dutta, Aditi, Wang, Shanqing, Chavez, Lukas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Final Category: Genomics/Epigenomics/Metabolomics - METB
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259935/ http://dx.doi.org/10.1093/neuonc/noad073.118

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