BIOL-09. PROTEOMIC ANALYSES REVEAL THAT CO-CULTURE OF DIFFUSE INTRINSIC PONTINE GLIOME (DIPG) WITH CORTICAL ORGANOIDS ALTERS CELL ADHESION, DNA SYNTHESIS AND REPLICATION, AND DENDRITIC GROWTH SIGNALLING

Diffuse Intrinsic Pontine Gliomas (DIPGs) are deadly brain cancers in children for which there is currently no effective treatment. In part, this can be attributed to preclinical models that lack essential elements of the in vivo tissue environment, resulting in treatments that appear promising prec...

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Detalles Bibliográficos
Autores principales: Prior, Victoria, Maksour, Simon, Miellet, Sara, Hulme, Amy, Mirzaei, Mehdi, Wu, Yunqi, Dottori, Mirella, O’Neill, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Basic Biology/Stem Cells/Models - BIOL
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259937/
http://dx.doi.org/10.1093/neuonc/noad073.028

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