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HGG-28. INTERIM ANALYSIS OF THE GCC1949 PHASE 2 TRIAL USING INDOXIMOD-BASED CHEMO-IMMUNOTHERAPY FOR PATIENTS WITH PEDIATRIC BRAIN TUMORS
Brain tumors are the leading cause of cancer-related death in children. We report interim results of an ongoing multi-institutional phase 2 trial (NCT04049669) of the IDO pathway-inhibitor indoximod utilized in a chemo-immunotherapy regimen for patients 3-21 years of age with either recurrent malign...
Autores principales: | Johnson, Theodore S, Pacholczyk, Rafal, Aguilera, Dolly, Berrong, Zuzana, Castellino, Robert C, Chi, Susan, Creager, Julianne, Eaton, Bree R, Fangusaro, Jason R, Huang, Chenbin, Hummel, Trent, Ingerski, Lisa, Kennedy, Eugene P, Ring, Eric, Sadek, Ramses F, Satpathy, Sarthak, Schniederjan, Matthew, Thomas, Beena E, Yeo, Kee Kiat, Bhasin, Manoj, MacDonald, Tobey J, Munn, David H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259940/ http://dx.doi.org/10.1093/neuonc/noad073.177 |
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