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CNSC-03. EXPLORING STRUCTURAL DISRUPTION OF TRICELLULAR JUNCTIONS TO ENHANCE BLOOD-BRAIN-BARRIER PERMEABILITY

The blood-brain barrier (BBB) hinders CNS chemotherapy entry for malignant glioma treatment. It is predominantly composed of brain endothelium linked by bicellular (BJ) and tricellular (TJ) tight junctions. Previous studies demonstrated,angubindin-1 inhibited TJ angulin-1 to increase brain and CSF t...

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Detalles Bibliográficos
Autores principales:	Cesaire, Melissa, Dalmage, Mahalia, Lim, Sanghee, Minhye, Kwak, Tang, Kayen, Conrad, Christina, Karim, Baktiar, Butcher, Donna, Jackson, Sadhana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Final Category: Cancer Neuroscience - CNSC
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259956/ http://dx.doi.org/10.1093/neuonc/noad073.046

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