EPEN-06. CHARACTERISING THE DEVELOPMENTAL ORIGINS AND TRAJECTORIES OF ZFTA-RELA FUSION EPENDYMOMA IN A NOVEL MOUSE MODEL

Ependymomas driven by the ZFTA-RELA fusion account for >70% of all supratentorial ependymomas. These tumours are now recognised in the WHO classification of CNS tumours and have been associated with a poor prognosis. Seven ZFTA-RELA fusion variants have been described: around two thirds of cases...

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Detalles Bibliográficos
Autores principales: Bonner, Sigourney, King, Claire, Rarhmann, Katherine Wickham, Cooper, Elizabeth, Katyal, Gunjan, Gilbertson, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Ependymoma - EPEN
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259970/
http://dx.doi.org/10.1093/neuonc/noad073.110

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