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ATRT-01. PARP INHIBITION AS A THERAPEUTIC TARGET IN ATRT

Atypical teratoid rhabdoid tumors (ATRTs) are highly aggressive pediatric brain tumors with poor survival. The available treatments rely on toxic chemotherapy and radiotherapy, which alone can cause poor outcomes for young patients. Poly (ADP-ribose) polymerases (PARP), multifunctional enzymes which...

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Detalles Bibliográficos
Autores principales:	Alimova, Irina, Mardok, Gillian, Pierce, Angela, Wang, Dong, Madhavan, Krishna, Brunt, Breauna, Vibhakar, Rajeev
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Final Category: ATRT/Embryonal/ETMR - ATRT
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259980/ http://dx.doi.org/10.1093/neuonc/noad073.001

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