ATRT-10. SINGLE-CELL TRANSCRIPTOME ANALYSIS REVEALS CELLULAR HIERARCHIES AND THERAPEUTIC VULNERABILITIES OF ETMR

Embryonal tumors with multilayered rosettes (ETMR) are malignant brain tumors that occur predominantly in infants and young children. Most patients die within two years of diagnosis, and more effective, targeted therapies are urgently needed. To better characterize the oncogenic mechanisms of key dr...

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Detalles Bibliográficos
Autores principales: Beck, Alexander, Gabler, Lisa, Cruzeiro, Gustavo A V, Lambo, Sander, Englinger, Bernhard, Shaw, McKenzie L, Hack, Olivia A, Liu, Ilon, Junior, Carlos A O de Biagi, Haase, Rebecca D, Klenner, Marbod, Freidel, Pia, Madlener, Sibylle, Mayr, Lisa, Senfter, Daniel, Peyrl, Andreas, Slavc, Irene, Lötsch, Daniela, Dorfer, Christian, Haberler, Christine, Pfister, Stefan M, Baird, Lissa, Chi, Susan N, Alexandrescu, Sanda, Gojo, Johannes, Kool, Marcel, Hovestadt, Volker, Filbin, Mariella G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: ATRT/Embryonal/ETMR - ATRT
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259985/
http://dx.doi.org/10.1093/neuonc/noad073.010

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