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OTHR-05. A LIVING EX VIVO PLATFORM FOR FUNCTIONAL, PERSONALIZED PEDIATRIC BRAIN CANCER DIAGNOSIS
Functional precision medicine platforms are emerging as promising strategies to improve pre-clinical drug testing and guide clinical decisions. We have developed an organotypic brain slice culture (OBSC)-based platform and multi-parametric algorithm which enable rapid engraftment, treatment, and ana...
Autores principales: | Mann, Breanna, Zhang, Xiaopei, Bell, Noah, Adefolaju, Adebimpe, Thang, Morrent, Dasari, Rajaneekar, Kanchi, Krishna, Valdivia, Alain, Yang, Yang, Quinsey, Carolyn, Rauf, Yasmeen, Kram, David, Cassidy, Noah, Viziri, Cyrus, Corcoran, David L, Rego, Stephan, Jiang, Yuchao, Graves, Lee M, Dunn, Denise, Floyd, Scott, Baldwin, Albert, Hingtgen, Shawn, Satterlee, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260012/ http://dx.doi.org/10.1093/neuonc/noad073.287 |
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